Organ transplantation comprises of many phases, processes, and activities and involves multiple stakeholders. Effective management of such a complex and costly medical domain requires an efficient, multifaceted solution. Although, Information Technology (IT) can basically play an important role here, it is not clear how IT potentials have been deployed so far. We systematically reviewed MEDLINE, EMBASE, CINAHL, The Cochrane and IEEE databases and identified 27 publications describing IT application in organ transplantation. Although the IT coverage spans over waiting list management, donor-recipient matching, and inpatient and outpatient medication and lab monitoring practices, the coverage is still patchy and whole process IT support is missing in practice.