Clinical study of anesthetization by dezocine combined with propofol for indolent colonoscopy

World J Gastroenterol. 2016 Jun 28;22(24):5609-15. doi: 10.3748/wjg.v22.i24.5609.


Aim: To assess the use of dezocine combined with propofol for the anesthetization of patients undergoing indolent colonoscopy.

Methods: A cross-sectional survey of patients undergoing indolent colonoscopy in the Xinjiang People's Hospital was conducted from April 1 to April 30, 2015. The survey collected patient general information and anesthesia data, including overall medical experience and pain management. Thirty minutes after colonoscopy surgery, samples of venous blood were collected and the biochemical indicators of gastrointestinal function were analyzed.

Results: There were 98 female and 62 male respondents. Indolent colonoscopy was found to be more suitable for mid to older-aged patients. The necessary conditions for the diagnosis of digestive diseases were required in 65 of the 73 inpatients. Adverse reactions to the intraoperative process included two cases of body movement and two cases of respiratory depression. Gastrin and vasoactive intestinal peptide levels were slightly increased. However, somatostatin and endothelin levels were slightly decreased.

Conclusion: This study revealed that dezocine combined with propofol can be successfully used for the anesthetization of indolent colonoscopy patients without pain and should be widely used.

Keywords: Anesthetization; Colonoscopy; Cross-sectional; Dezocine; Patient assessment; Propofol.

Publication types

  • Observational Study

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Analgesics, Opioid / therapeutic use*
  • Anesthetics, Intravenous / therapeutic use*
  • Bridged Bicyclo Compounds, Heterocyclic / therapeutic use*
  • Child
  • Child, Preschool
  • Colonoscopy / methods*
  • Conscious Sedation / methods*
  • Cross-Sectional Studies
  • Female
  • Humans
  • Infant
  • Male
  • Middle Aged
  • Propofol / therapeutic use*
  • Tetrahydronaphthalenes / therapeutic use*
  • Young Adult


  • Analgesics, Opioid
  • Anesthetics, Intravenous
  • Bridged Bicyclo Compounds, Heterocyclic
  • Tetrahydronaphthalenes
  • dezocine
  • Propofol