Salicylate-induced rhabdomyolysis

Am J Emerg Med. 1989 Jul;7(4):409-10. doi: 10.1016/0735-6757(89)90049-1.


A 42-year-old woman was hospitalized with aspirin intoxication. The patient developed massive skeletal muscle damage without any evidence of muscle compression, hyperthermia, or other predisposing factors. The exact mechanism by which salicylates cause muscle damage is unknown, but the muscle damage appears to be the result of a direct toxic effect. This represents the first case of isolated salicylate-induced rhabdomyolysis.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Aspirin / poisoning*
  • Female
  • Gastric Lavage
  • Humans
  • Renal Dialysis
  • Rhabdomyolysis / chemically induced*
  • Rhabdomyolysis / therapy
  • Suicide, Attempted


  • Aspirin