The memory-enhancing effects of the piracetam-like nootropics are dependent on experimental parameters

Behav Brain Res. 1989 May 1;33(1):79-82. doi: 10.1016/s0166-4328(89)80020-8.

Abstract

The effects of the nootropic agent piracetam and its congeners oxiracetam, pramiracetam and aniracetam on the retention performance of mice in a passive-avoidance situation are dependent on the intensity of the foot-shock applied. This phenomenon is observed upon both pre-trial and post-trial drug administration.

Publication types

  • Comparative Study

MeSH terms

  • Animals
  • Avoidance Learning / drug effects*
  • Dose-Response Relationship, Drug
  • Male
  • Memory / drug effects*
  • Mental Recall / drug effects*
  • Mice
  • Mice, Inbred Strains
  • Piracetam / pharmacology*
  • Pyrrolidines / pharmacology
  • Pyrrolidinones / pharmacology*

Substances

  • Pyrrolidines
  • Pyrrolidinones
  • pramiracetam
  • aniracetam
  • oxiracetam
  • Piracetam