Synthetic Fillers for Facial Rejuvenation

Johnson C Lee; Z Paul Lorenc

doi:10.1016/j.cps.2016.03.002

Synthetic Fillers for Facial Rejuvenation

Clin Plast Surg. 2016 Jul;43(3):497-503. doi: 10.1016/j.cps.2016.03.002.

Authors

Johnson C Lee¹, Z Paul Lorenc²

Affiliations

¹ Private Practice, Enhance Medical Center, 462 North Linden Drive, Suite 333, Beverly Hills, CA 90212, USA. Electronic address: JCLMD@enhancemedicalcenter.com.
² Lorenc Aesthetic Plastic Surgery Center, 983 Park Avenue, New York, NY 10028, USA.

PMID: 27363763
DOI: 10.1016/j.cps.2016.03.002

Abstract

Soft tissue filler procedures have increased dramatically in popularity in the United States. Synthetic fillers such as calcium hydroxyapatite (CaHA), polymethyl methacrylate (PMMA), and poly-l-lactic acid (PLLA), and silicone provide initial volume replacement but have an additional biostimulatory effect to supplement facial volumization. Indications include human immunodeficiency virus lipoatrophy and nasolabial folds for CaHA and PLLA and atrophic acne scars for PMMA. Most clinical use of these synthetic fillers is in an off-label fashion. Beyond the proper choice of a synthetic filler, careful consideration of dilution, injection method, and postprocedural care allows for successful and consistent results.

Keywords: CaHA; Fillers; Injectables; PLLA; PMMA; Silicone; Synthetic.

Publication types

Review

MeSH terms

Cosmetic Techniques*
Dermal Fillers / therapeutic use*
Durapatite / therapeutic use
Face
Humans
Injections, Subcutaneous
Polyesters / therapeutic use
Polymethyl Methacrylate / therapeutic use
Rejuvenation*
Silicone Oils / therapeutic use
Skin Aging*

Substances

Dermal Fillers
Polyesters
Silicone Oils
poly(lactide)
Polymethyl Methacrylate
Durapatite