Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Clinical Trial
. 1989 Apr;22(4):759-62.
doi: 10.1016/0361-9230(89)90096-8.

Treatment With Tyrosine, a Neurotransmitter Precursor, Reduces Environmental Stress in Humans

Affiliations
Clinical Trial

Treatment With Tyrosine, a Neurotransmitter Precursor, Reduces Environmental Stress in Humans

L E Banderet et al. Brain Res Bull. .

Abstract

Acutely stressful situations can disrupt behavior and deplete brain norepinephrine and dopamine, catecholaminergic neurotransmitters. In animals, administration of tyrosine, a food constituent and precursor of the catecholamines, reduces these behavioral and neurochemical deficits. Using a double-blind, placebo-controlled crossover design we investigated whether tyrosine (100 mg/kg) would protect humans from some of the adverse consequences of a 4.5 hour exposure to cold and hypoxia. Tyrosine significantly decreased symptoms, adverse moods, and performance impairments in subjects who exhibited average or greater responses to these environmental conditions. These results suggest that tyrosine should be evaluated in a variety of acutely stressful situations.

Similar articles

See all similar articles

Cited by 21 articles

See all "Cited by" articles

Publication types

LinkOut - more resources

Feedback