Comparison of real and placebo acupuncture in histamine-induced asthma. A double-blind crossover study

Chest. 1989 Jul;96(1):102-5. doi: 10.1378/chest.96.1.102.


A double-blind crossover study of the effects of real and placebo acupuncture on bronchial reactivity to histamine was carried out on 16 patients with moderately severe asthma. Treatment with real or placebo acupuncture failed to modulate the bronchial hyperreactivity to histamine. These results suggest that a single treatment with acupuncture is unlikely to provide improvement in the management of acute bronchial asthma.

Publication types

  • Clinical Trial
  • Comparative Study
  • Controlled Clinical Trial

MeSH terms

  • Acupuncture Therapy*
  • Adult
  • Asthma / diagnosis
  • Asthma / therapy*
  • Bronchial Provocation Tests*
  • Double-Blind Method
  • Female
  • Histamine
  • Humans
  • Male
  • Placebos


  • Placebos
  • Histamine