Outcomes After Surgical Pulmonary Embolectomy for Acute Pulmonary Embolus: A Multi-Institutional Study

Ann Thorac Surg. 2016 Nov;102(5):1498-1502. doi: 10.1016/j.athoracsur.2016.05.004. Epub 2016 Jun 30.

Abstract

Background: Surgical pulmonary embolectomy (SPE) has been sparingly used for the successful treatment of massive and submassive pulmonary emboli. To date, all data regarding SPE have been limited to single-center experiences. The purpose of this study was to document short-term outcomes after SPE for acute pulmonary emboli (PE) at four high-volume institutions.

Methods: A retrospective review of multiple local Society of Thoracic Surgeons databases of adults undergoing SPE from 1998 to 2014 for acute PE was performed (n = 214). Demographic, operative, and outcomes data were collected and analyzed. Patients were summarily categorized as having either massive or submassive PEs based on the presence or absence of preoperative vasopressors.

Results: A total of 214 patients with acute PE were treated by SPE. The mean age was 56.0 ± 14.5 years, and 92 (43.6%) patients were female. Of those, 176 (82.2%) PEs were submassive and 38 (17.8%) were massive. Fifteen (7.0%) patients underwent concomitant cardiac procedures, with 10 (4.7%) having simultaneous valvular interventions and 5 (2.4%) undergoing concomitant bypass grafting. Cardiopulmonary bypass (CPB) was used for all cases. Cardioplegic arrest was used for 80 (37.4%) patients. The median CPB and aortic cross clamp times were 71.5 (interquartile range [IQR], 47.0-109.5) and 46.0 (IQR, 26.0-74.5), respectively. Notably, only 25 (11.7%) patients died in the hospital. Mortality was highest among the 28 patients who experienced preoperative cardiac arrest (9, 32.1%) CONCLUSIONS: These data represent the first multicenter experience with SPE for acute pulmonary emboli. Surgical pulmonary embolectomy for acute massive and submassive PE is safe and can be performed with acceptable in-hospital outcomes; the procedure should be included in the multimodality treatment of life-threatening pulmonary emboli.

Publication types

  • Evaluation Study
  • Multicenter Study

MeSH terms

  • Acute Disease
  • Adult
  • Aged
  • Combined Modality Therapy
  • Comorbidity
  • Coronary Artery Bypass / statistics & numerical data
  • Embolectomy / methods*
  • Embolectomy / mortality
  • Embolectomy / statistics & numerical data
  • Female
  • Heart Arrest / epidemiology
  • Heart Valve Prosthesis Implantation / statistics & numerical data
  • Hospitals, High-Volume
  • Humans
  • Male
  • Middle Aged
  • Postoperative Complications / epidemiology
  • Pulmonary Embolism / drug therapy
  • Pulmonary Embolism / surgery*
  • Retrospective Studies
  • Thrombolytic Therapy
  • Treatment Outcome