Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2016 Jun 7;6:140.
doi: 10.3389/fonc.2016.00140. eCollection 2016.

The Emerging Role of Carbon-Ion Radiotherapy

Affiliations
Free PMC article

The Emerging Role of Carbon-Ion Radiotherapy

Daniel K Ebner et al. Front Oncol. .
Free PMC article

Abstract

Carbon-ion radiotherapy (CIRT) has progressed rapidly in technological delivery, indications, and efficacy. Owing to a focused dose distribution in addition to high linear energy transfer and subsequently high relative biological effect, CIRT is uniquely able to target otherwise untreatable hypoxic and radioresistant disease while opening the door for substantially hypofractionated treatment of normal and radiosensitive disease. CIRT has increasingly garnered international attention and is nearing the tipping point for international adoption.

Keywords: adaptation; carbon-ion radiotherapy; particle beam therapy; performance; radioresistance.

Figures

Figure 1
Figure 1
Dose distribution of heavy-particle beams.

Similar articles

See all similar articles

Cited by 13 articles

See all "Cited by" articles

References

    1. Tobias CA, Anger HO, Lawrence JH. Radiological use of high energy deuterons and alpha particles. Am J Roentgenol Radium Ther Nucl Med (1952) 67:1–27. - PubMed
    1. Curtis SB. Plans for the high-energy, heavy-ion facility (BEVALAC) at Berkeley. Eur J Cancer (1974) 10:388. - PubMed
    1. Castro JR, Quivey JM, Lyman JT, Chen G, Phillips TL, Tobias CA. Radiotherapy with heavy charged-particles at Lawrence Berkeley Laboratory. J Can Assoc Radiol (1980) 31:30–4. - PubMed
    1. Kraft G. History of the Heavy Ion Therapy at GSI. (2013). p. 1–17. Available from: https://three.jsc.nasa.gov/articles/Krafts_GSI.pdf
    1. Kanai T, Endo M, Minohara S, Miyahara N, Koyama-ito H, Tomura H, et al. Biophysical characteristics of HIMAC clinical irradiation system for heavy-ion radiation therapy. Radiat Oncol Biol (1999) 44:201–10.10.1016/S0360-3016(98)00544-6 - DOI - PubMed

LinkOut - more resources

Feedback