Caffeine consumption, insomnia, and sleep duration: Results from a nationally representative sample

Nutrition. Nov-Dec 2016;32(11-12):1193-9. doi: 10.1016/j.nut.2016.04.005. Epub 2016 May 10.

Abstract

Objective: Insomnia symptoms have been individually associated with both caffeine consumption and sleep duration abnormalities in prior studies. The goal of this study was to determine whether caffeine consumption was associated with insomnia symptoms from a population perspective and whether this relationship depended on habitual sleep duration.

Methods: Data were extracted from the 2007-2008 National Health and Nutritional Examination Survey (N = 4730). Caffeine consumption was quantified as mg/d from 2 typical days of use, 7 to 10 d apart. Insomnia symptoms were evaluated using frequencies of difficulty falling asleep (DFA), difficulty staying asleep (DSA), non-restorative sleep (NRS), and daytime sleepiness (DS). Habitual sleep duration was assessed as the hours of sleep obtained on a typical night. Binomial logistic regression analysis evaluated the relationships of individual insomnia and sleepiness symptoms (DFA, DSA, NRS, and DS) with caffeine consumption and sleep duration variables, after adjusting for covariates.

Results: The mean ± SD caffeine consumption was 176.6 ± 201 mg/d. Mean habitual sleep duration was 6.8 ± 1.4 h. Insomnia symptoms were prevalent in 19.1% to 28.4% of the respondents. Although caffeine consumption was associated with all insomnia symptoms in the unadjusted models, the adjusted models demonstrated a trend toward significance with DSA. Sleep duration was inversely associated with the insomnia symptoms in unadjusted and adjusted analysis. Finally, NRS was associated with an interaction between increased caffeine consumption and sleep duration.

Conclusion: The association between caffeine use and insomnia symptoms depends on habitual sleep duration at a population level.

Keywords: Anxiety; Caffeine; Population; Sleep deprivation; Sleep initiation and maintenance disturbance.

MeSH terms

  • Adult
  • Caffeine / administration & dosage*
  • Caffeine / adverse effects*
  • Central Nervous System Stimulants / administration & dosage
  • Central Nervous System Stimulants / adverse effects
  • Female
  • Humans
  • Male
  • Middle Aged
  • Nutrition Surveys
  • Prevalence
  • Sleep / drug effects*
  • Sleep / physiology
  • Sleep Initiation and Maintenance Disorders / epidemiology
  • Sleep Initiation and Maintenance Disorders / etiology*
  • Sleep Initiation and Maintenance Disorders / physiopathology*
  • United States / epidemiology
  • Young Adult

Substances

  • Central Nervous System Stimulants
  • Caffeine