Flavonol Glycosides From the Aerial Parts of Gynostemma Pentaphyllum and Their Antioxidant Activity

Arch Pharm Res. 2016 Sep;39(9):1232-6. doi: 10.1007/s12272-016-0793-x. Epub 2016 Jul 6.

Abstract

The phytochemical investigation of the aerial parts of Gynostemma pentaphyllum led to the isolation of a new flavonol glycoside, gynopentaphylloside (1), along with seven known compounds (2-8). The structure of the new compound was determined on the basis of 1D, 2D NMR and HRESIMS data as well as acid hydrolysis. The antioxidant activity of the isolates was evaluated by a 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging assay.

Keywords: Antioxidant activity; Cucurbitaceae; Flavonol glycoside; Gynostemma pentaphyllum.

MeSH terms

  • Antioxidants / chemistry*
  • Antioxidants / isolation & purification
  • Antioxidants / pharmacology
  • Flavonols / chemistry*
  • Flavonols / isolation & purification
  • Flavonols / pharmacology
  • Free Radical Scavengers / chemistry
  • Free Radical Scavengers / isolation & purification
  • Free Radical Scavengers / pharmacology
  • Glycosides / chemistry*
  • Glycosides / isolation & purification
  • Glycosides / pharmacology
  • Gynostemma*
  • Oxidation-Reduction / drug effects
  • Plant Components, Aerial*
  • Plant Extracts / chemistry*
  • Plant Extracts / isolation & purification
  • Plant Extracts / pharmacology

Substances

  • Antioxidants
  • Flavonols
  • Free Radical Scavengers
  • Glycosides
  • Plant Extracts