The correlation between organoleptic mouth-odor ratings and levels of volatile sulfur compounds

Oral Surg Oral Med Oral Pathol. 1978 Apr;45(4):560-7. doi: 10.1016/0030-4220(78)90037-3.


An organoleptic rating (OR) technique and gas-liquid chromatography were employed to study the relationship between oral-malodor ratings and the corresponding concentrations of oral volatile sulfur compounds (VSC) in a total of 102 subjects in two separate studies. Both studies demonstrated a statistically significant positive correlation between the intensity of perceived oral malodor and the concentration of VSC (H2S + CH3SH) emitted by individual subjects.

MeSH terms

  • Chromatography, Gas
  • Female
  • Halitosis / metabolism
  • Halitosis / physiopathology*
  • Humans
  • Hydrogen Sulfide / analysis*
  • Male
  • Odorants* / analysis
  • Saliva / analysis
  • Sulfhydryl Compounds / analysis*


  • Sulfhydryl Compounds
  • Hydrogen Sulfide