Closing the net on retroviruses

Elife. 2016 Jul 7:5:e18243. doi: 10.7554/eLife.18243.

Abstract

Structural studies reveal how an antiviral factor forms a molecular net to restrict retroviruses including HIV-1.

Keywords: HIV; TRIM5; biophysics; capsid; higher-order assembly; human; infectious disease; microbiology; protein structure; restriction factor; rhesus macaque; structural biology; virus.

Publication types

  • Comment

MeSH terms

  • Animals
  • Capsid*
  • Carrier Proteins
  • HIV-1*
  • Macaca mulatta
  • Retroviridae
  • Retroviridae Proteins

Substances

  • Carrier Proteins
  • Retroviridae Proteins