Diagnosis and management of benign fibro-osseous lesions of the jaws: a current review for the dental clinician

Oral Dis. 2017 May;23(4):440-450. doi: 10.1111/odi.12531. Epub 2016 Aug 1.


Benign fibro-osseous lesions of the maxillofacial skeleton constitute a heterogeneous group of disorders that includes developmental, reactive (dysplastic) and neoplastic lesions. Although their classification has been reviewed multiple times in the past, the most common benign fibro-osseous lesions are fibrous dysplasia, osseous dysplasia and ossifying fibroma. For the dental clinician, the challenges involve diagnosis and treatment (or lack thereof). A careful correlation of all clinical, radiologic and microscopic features is essential to establish a proper diagnosis and a clear treatment plan. This article aimed to review the clinical, radiologic and histopathologic characteristics of benign fibro-osseous lesions of the jaws, with emphasis on their differential diagnoses. With a deeper understanding of benign fibro-osseous lesions, clinicians will be better prepared to manage these lesions in their practice.

Keywords: benign fibro-osseous lesions; familial gigantiform cementoma; fibrous dysplasia; juvenile ossifying fibroma; osseous dysplasia; ossifying fibroma.

Publication types

  • Review

MeSH terms

  • Cementoma* / diagnosis
  • Cementoma* / pathology
  • Cementoma* / therapy
  • Diagnosis, Differential
  • Fibroma, Ossifying* / diagnosis
  • Fibroma, Ossifying* / pathology
  • Fibroma, Ossifying* / therapy
  • Fibrous Dysplasia of Bone* / diagnosis
  • Fibrous Dysplasia of Bone* / pathology
  • Fibrous Dysplasia of Bone* / therapy
  • General Practice, Dental
  • Humans
  • Jaw Neoplasms* / diagnosis
  • Jaw Neoplasms* / pathology
  • Jaw Neoplasms* / therapy

Supplementary concepts

  • Gigantiform Cementoma, Familial