Heat Shock Factor 1: From Fire Chief to Crowd-Control Specialist

Mol Cell. 2016 Jul 7;63(1):1-2. doi: 10.1016/j.molcel.2016.06.026.


HSF1 is the supposed master regulator of the heat shock response. In this issue of Molecular Cell, Solís et al. reveal that it has a much narrower job description: organizing a small team of molecular chaperones that keep the proteome moving.

Publication types

  • Comment

MeSH terms

  • DNA-Binding Proteins*
  • Heat-Shock Proteins
  • Heat-Shock Response
  • Humans
  • Molecular Chaperones
  • Transcription Factors*


  • DNA-Binding Proteins
  • Heat-Shock Proteins
  • Molecular Chaperones
  • Transcription Factors