Thinking Systematically About the Off-Label Use of Cancer Drugs and Combinations for Patients Who Have Exhausted Proven Therapies

Oncologist. 2016 Sep;21(9):1031-2. doi: 10.1634/theoncologist.2016-0086. Epub 2016 Jul 8.


This article explores the circumstances under which providers and patients should be able to attempt drugs or combinations for indications for which we still lack formal clinical trials.

MeSH terms

  • Antineoplastic Agents / therapeutic use*
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
  • Clinical Trials as Topic
  • Humans
  • Neoplasms / drug therapy*
  • Off-Label Use


  • Antineoplastic Agents