Pink Light on Mitochondria in Autoimmunity and Parkinson Disease

Cell Metab. 2016 Jul 12;24(1):11-2. doi: 10.1016/j.cmet.2016.06.022.


Mitochondrial dysfunction and T cell autoimmunity have been independently implicated in Parkinson disease pathogenesis. In a recent publication in Cell, Matheoud et al. (2016) link them by describing a new mechanism, activated in familial forms of Parkinson disease, in which mitochondrial proteins are processed for recognition by CD8+ T cells.

Publication types

  • Comment

MeSH terms

  • Autoimmunity*
  • Humans
  • Mitochondria
  • Mitochondrial Proteins
  • Parkinson Disease*


  • Mitochondrial Proteins