Fast-Track Clearance of Bacteria from the Liver

Cristina Llorente; Bernd Schnabl

doi:10.1016/j.chom.2016.06.012

Fast-Track Clearance of Bacteria from the Liver

Cell Host Microbe. 2016 Jul 13;20(1):1-2. doi: 10.1016/j.chom.2016.06.012.

Authors

Cristina Llorente¹, Bernd Schnabl²

Affiliations

¹ Department of Medicine, University of California San Diego, La Jolla, CA 92093, USA; Department of Medicine, VA San Diego Healthcare System, San Diego, CA 92161, USA.
² Department of Medicine, University of California San Diego, La Jolla, CA 92093, USA; Department of Medicine, VA San Diego Healthcare System, San Diego, CA 92161, USA. Electronic address: beschnabl@ucsd.edu.

PMID: 27414492
DOI: 10.1016/j.chom.2016.06.012

Abstract

The liver plays a central role in clearing bacteria from the bloodstream. Two articles in this issue of Cell Host & Microbe (Broadley et al., 2016; Zeng et al., 2016) identify new mechanisms by which resident liver macrophages (Kupffer cells) rapidly capture bacteria from the blood and eliminate them, while still allowing for the induction of adaptive immunity.

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MeSH terms

Adaptive Immunity
Bacteria
Humans
Kupffer Cells / immunology*
Liver / immunology*