We studied the results of sanatorium treatment of 256 patients with complicated spinal injury and decubital ulcers. 74% of patients were male patients aged 38.5 ± 11.8 years. 89.4% of patients suffered from severe abnormalities, mild abnormalities were registered in 10.6% of patients. In 82.6% of patients decubital ulcers were localized to the skin only on one site, in 17.4% was registered multiple localization. Duration of the patients'follow-up varied from one to three years or more. Patients were divided into 2 clinical groups: the first group consisted of 132 patients who were applied during the preoperative preparation balneological factors and nanosilver, 124 patients included in the second group, which preoperative preparation was carried out in conventional-manner. Using complex medical factors in preparation for operations contributed to reducing the duration of training from 26 ± 3 days to 14 ± 2 days. The application of complex restorative treatment system allowed in the first group compared with the second group increased the number of patients with good results.