Metronidazole Metabolism in Neonates and the Interplay Between Ontogeny and Genetic Variation

J Clin Pharmacol. 2017 Feb;57(2):230-234. doi: 10.1002/jcph.797. Epub 2016 Aug 23.
No abstract available

Publication types

  • Multicenter Study
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Anti-Infective Agents / metabolism*
  • Anti-Infective Agents / pharmacokinetics*
  • Cohort Studies
  • Cytochrome P-450 Enzyme System / genetics*
  • Cytochrome P-450 Enzyme System / metabolism
  • Female
  • Genetic Variation*
  • Humans
  • Infant, Newborn
  • Male
  • Metronidazole / metabolism*
  • Metronidazole / pharmacokinetics*

Substances

  • Anti-Infective Agents
  • Metronidazole
  • Cytochrome P-450 Enzyme System