At the double for tumor suppressor

Elife. 2016 Jul 15:5:e18391. doi: 10.7554/eLife.18391.

Abstract

Research on zebrafish reveals how a tumor suppressor works in two different types of cells, and how hypotonic stress promotes tumor formation when the function of this tumor suppressor is lost.

Keywords: Na/K-ATPase; cancer biology; carcinogenesis; developmental biology; epithelial polarity; stem cells; zebrafish.

Publication types

  • Comment

MeSH terms

  • Animals
  • Genes, Tumor Suppressor
  • Keratinocytes*
  • Sodium
  • Sodium-Potassium-Exchanging ATPase / genetics*
  • Zebrafish

Substances

  • Sodium
  • Sodium-Potassium-Exchanging ATPase