Cerebellar and Brainstem Malformations

Neuroimaging Clin N Am. 2016 Aug;26(3):341-57. doi: 10.1016/j.nic.2016.03.005.


The frequency and importance of the evaluation of the posterior fossa have increased significantly over the past 20 years owing to advances in neuroimaging. Conventional and advanced neuroimaging techniques allow detailed evaluation of the complex anatomic structures within the posterior fossa. A wide spectrum of cerebellar and brainstem malformations has been shown. Familiarity with the spectrum of cerebellar and brainstem malformations and their well-defined diagnostic criteria is crucial for optimal therapy, an accurate prognosis, and correct genetic counseling. This article discusses cerebellar and brainstem malformations, with emphasis on neuroimaging findings (including diagnostic criteria), neurologic presentation, systemic involvement, prognosis, and recurrence.

Keywords: Brain stem; Cerebellum; Children; Diffusion tensor imaging; Malformation; Neuroimaging.

Publication types

  • Review

MeSH terms

  • Brain Stem / abnormalities*
  • Brain Stem / diagnostic imaging*
  • Cerebellar Diseases / diagnostic imaging*
  • Cerebellum / abnormalities*
  • Cerebellum / diagnostic imaging*
  • Humans
  • Magnetic Resonance Imaging / methods
  • Neuroimaging / methods*