Online interactive analysis of protein structure ensembles with Bio3D-web

Bioinformatics. 2016 Nov 15;32(22):3510-3512. doi: 10.1093/bioinformatics/btw482. Epub 2016 Jul 16.


Bio3D-web is an online application for analyzing the sequence, structure and conformational heterogeneity of protein families. Major functionality is provided for identifying protein structure sets for analysis, their alignment and refined structure superposition, sequence and structure conservation analysis, mapping and clustering of conformations and the quantitative comparison of their predicted structural dynamics.

Availability: Bio3D-web is based on the Bio3D and Shiny R packages. All major browsers are supported and full source code is available under a GPL2 license from CONTACT: or

MeSH terms

  • Data Interpretation, Statistical
  • Programming Languages
  • Proteins*
  • Sequence Alignment
  • Software*


  • Proteins