Late-onset sepsis due to Staphylococcus capitis 'neonatalis' in low-birthweight infants: a new entity?

J Hosp Infect. 2016 Sep;94(1):95-8. doi: 10.1016/j.jhin.2016.06.008. Epub 2016 Jun 17.

Abstract

During hospitalization, sepsis occurs in one of every five very-low-birthweight infants. The emergence of Staphylococcus capitis (SC)-related sepsis in preterm infants was observed recently. This study aimed to evaluate the clinical severity of SC-related sepsis in preterm infants. Of the 105 infants who presented with sepsis related to coagulase-negative staphylococci, 74 were SC. Severe morbidity was more common in the SC group (55.4%) than in the non-SC coagulase-negative staphylococci group (32.0%) (P=0.03). Multi-variate analysis identified SC-related sepsis as an independent risk factor for severe morbidity.

Keywords: Morbidity; Prematurity; Sepsis; Staphylococcus.

MeSH terms

  • Female
  • Humans
  • Infant
  • Infant, Low Birth Weight*
  • Infant, Newborn
  • Late Onset Disorders / epidemiology*
  • Late Onset Disorders / microbiology
  • Late Onset Disorders / pathology
  • Male
  • Neonatal Sepsis / epidemiology*
  • Neonatal Sepsis / microbiology
  • Neonatal Sepsis / pathology
  • Prospective Studies
  • Staphylococcal Infections / epidemiology*
  • Staphylococcal Infections / microbiology
  • Staphylococcal Infections / pathology
  • Staphylococcus / classification
  • Staphylococcus / isolation & purification*