A new device for the simultaneous recording of cerebral, cardiac, and muscular electrical activity in freely moving rodents

J Pharmacol Sci. 2016 Sep;132(1):105-108. doi: 10.1016/j.jphs.2016.06.001. Epub 2016 Jun 23.


We present a new technique for the simultaneous capture of bioelectrical time signals from the brain and peripheral organs of freely moving rodents. The recording system integrates all systemic signals into an electrical interface board that is mounted on an animal's head for an extended period. The interface board accommodates up to 48 channels, enabling us to analyze neuronal activity patterns in multiple brain regions by comparing a variety of physiological body states over weeks and months. This technique will advance the understanding of the neurophysiological correlate of mind-body associations in health and disease.

Keywords: Electromyogram; Heart rate; Local field potential.

MeSH terms

  • Animals
  • Brain / physiology*
  • Electrocardiography / instrumentation*
  • Electromyography / instrumentation*
  • Electrophysiological Phenomena
  • Equipment Design
  • Heart / physiology*
  • Mice
  • Muscle, Skeletal / physiology*
  • Neurons / physiology
  • Rats