Chondroitin sulfate derived theranostic nanoparticles for targeted drug delivery

Biomater Sci. 2016 Aug 16;4(9):1310-3. doi: 10.1039/c6bm00335d.


Glycosaminoglycan derived nanoparticles are a promising delivery system owing to their unique tumour targeting ability. Exploiting fluorescein for inducing amphiphilicity in these biopolymers provides inherent imaging and drug stabilization capabilities by π-π stacking interactions with aromatic antineoplastic agents. This offers a versatile and highly customizable nanocarrier with narrow size distribution and high drug loading efficiency (80%) with sustained drug release.

MeSH terms

  • Chondroitin Sulfates / chemistry*
  • Drug Carriers / chemistry
  • Drug Delivery Systems / methods*
  • Nanoparticles / chemistry*
  • Theranostic Nanomedicine / methods*


  • Drug Carriers
  • Chondroitin Sulfates