Intra-axial brain tumors

Handb Clin Neurol. 2016:135:253-274. doi: 10.1016/B978-0-444-53485-9.00014-3.


There is a wide variety of intra-axial primary and secondary brain neoplasms. Many of them have characteristic imaging features while other tumors can present in a similar fashion. There are peculiar posttreatment imaging phenomena that can present as intra-axial mass-like lesions (such as pseudoprogression or radiation necrosis), further complicating the diagnosis and clinical follow-up of patients with intracerebral tumors. The purpose of this chapter is to present a general overview of the most common intra-axial brain tumors and peculiar posttreatment changes that are very important in the diagnosis and clinical follow-up of patients with brain tumors.

Keywords: astrocytoma; cerebral metastases; choroid plexus tumor; ependymoma; glioblastoma; gliomas; intra-axial brain tumor; medulloblastoma; oligodendroglioma; primitive neuroectodermal tumors.

MeSH terms

  • Angiogenesis Inhibitors / therapeutic use
  • Brain Neoplasms / classification*
  • Brain Neoplasms / diagnosis*
  • Brain Neoplasms / epidemiology
  • Brain Neoplasms / therapy
  • Brain* / diagnostic imaging
  • Brain* / pathology
  • Glioma / classification
  • Glioma / diagnosis
  • Glioma / therapy
  • Humans
  • Necrosis / diagnostic imaging
  • Necrosis / etiology
  • Neuroimaging*


  • Angiogenesis Inhibitors