Multimodal Imaging in Acute Posterior Multifocal Placoid Pigment Epitheliopathy Demonstrating Obstruction of the Choriocapillaris

Ophthalmic Surg Lasers Imaging Retina. 2016 Jul 1;47(7):677-81. doi: 10.3928/23258160-20160707-12.


Optical coherence tomography angiography (OCTA) provides noninvasive in vivo vascular imaging of the retina and choriocapillaris. To highlight OCTA utility, the authors align structural changes and their resolution with functional outcome. The authors present a case of acute posterior multifocal placoid pigment epitheliopathy (APMPPE) and sequential changes during transition to inactive disease. In the acute phase, altered flow and nonperfusion were seen in defined islands of choriocapillaris. Over time, progressive reperfusion was observed and accompanied clinical resolution and functional visual restoration. The imaging features acquired described the level of nonperfusion the authors had assumed when extrapolating findings from multiple independent imaging modalities. [Ophthalmic Surg Lasers Imaging Retina. 2016;47:677-681.].

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acute Disease
  • Adult
  • Capillaries / pathology*
  • Choroid / blood supply*
  • Constriction, Pathologic / diagnosis
  • Fluorescein Angiography / methods
  • Fundus Oculi
  • Humans
  • Male
  • Multimodal Imaging / methods*
  • Pigment Epithelium of Eye / pathology*
  • Retinal Diseases
  • Tomography, Optical Coherence / methods