Group 4 Pulmonary Hypertension: Chronic Thromboembolic Pulmonary Hypertension: Epidemiology, Pathophysiology, and Treatment

Cardiol Clin. 2016 Aug;34(3):435-41. doi: 10.1016/j.ccl.2016.04.011.


Chronic thromboembolic pulmonary hypertension (CTEPH) is a serious but treatable complication of pulmonary embolism. Proper diagnosis and referral are critical, as pulmonary thromboendarterectomy offers the possibility of a cure. For patients with CTEPH deemed inoperable, new and effective treatments have emerged to help fill this unmet need.

Keywords: Balloon pulmonary angioplasty; Chronic thromboembolic pulmonary hypertension; Chronic thromboembolism; Pulmonary embolism; Pulmonary endarterectomy; Pulmonary thromboendarterectomy; Riociguat.

Publication types

  • Review

MeSH terms

  • Angioplasty, Balloon / methods*
  • Embolectomy / methods*
  • Endarterectomy
  • Global Health
  • Humans
  • Hypertension, Pulmonary* / epidemiology
  • Hypertension, Pulmonary* / etiology
  • Hypertension, Pulmonary* / surgery
  • Morbidity / trends
  • Pulmonary Artery / surgery*
  • Pulmonary Embolism* / complications
  • Pulmonary Embolism* / epidemiology
  • Pulmonary Embolism* / surgery
  • Pulmonary Wedge Pressure / physiology*