The gene for human complement component C9 mapped to chromosome 5 by polymerase chain reaction

Genomics. 1989 May;4(4):606-9. doi: 10.1016/0888-7543(89)90286-3.

Abstract

The gene for human complement component C9 has been mapped to chromosome 5. This was achieved by using a novel application of the polymerase chain reaction to amplify specifically the human C9 gene on a background of rodent DNA in somatic cell hybrids. The assignment to chromosome 5 was confirmed by in situ hybridization to human metaphase chromosomes, giving a regional localization of 5p13.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Chromosome Mapping
  • Chromosomes, Human, Pair 5*
  • Complement C9 / genetics*
  • Cricetinae
  • Cricetulus
  • Gene Amplification
  • Genes
  • Humans
  • Hybrid Cells
  • Mice
  • Rats

Substances

  • Complement C9