Tendinous Laxity and Jaccoud's Syndrome in Patients With Systemic Lupus Erythematosus. Possible Role of Secondary Hyperparathyroidism

J Rheumatol. 1989 Apr;16(4):494-8.

Abstract

Fourteen of 52 unselected patients with systemic lupus erythematosus (SLE) (27%) had ligamentous derangement demonstrated by either Jaccoud's syndrome and/or patellar tendon elongation. Three cases had only Jaccoud's syndrome, 4 isolated patellar tendinous laxity, while the remaining 7 presented both findings. Jaccoud's syndrome and/or tendinous laxity were not associated to an increased frequency of arthritis, corticosteroid therapy or a longer disease duration, but significantly associated with increased serum PTH levels secondary to chronic renal failure. Hyperparathyroidism secondary to chronic renal failure should, therefore, be considered a potential factor contributing to the development of Jaccoud's syndrome and/or tendinous laxity in patients with SLE.

MeSH terms

  • Adolescent
  • Adult
  • Arthritis / physiopathology*
  • Calcium / blood
  • Child
  • Creatinine / urine
  • Female
  • Foot Deformities, Congenital
  • Hand Deformities, Congenital
  • Humans
  • Hyperparathyroidism, Secondary / physiopathology*
  • Joint Instability / physiopathology*
  • Knee Joint / physiopathology
  • Lupus Erythematosus, Systemic / physiopathology*
  • Male
  • Middle Aged
  • Parathyroid Hormone / blood
  • Phosphorus / blood
  • Tendons / physiopathology*
  • Uric Acid / blood

Substances

  • Parathyroid Hormone
  • Uric Acid
  • Phosphorus
  • Creatinine
  • Calcium