Small intestinal perforation in Wegener's granulomatosis

J Rheumatol. 1989 Apr;16(4):547-9.


Wegener's granulomatosis is a disease characterized by necrotizing vasculitis and granulomatous inflammation. Gastrointestinal (GI) involvement is uncommon in this disorder. Only a few cases of perforation of GI tract have been reported, but vasculitis has not been demonstrated to be a cause of perforation in these cases. We report a case of Wegener's granulomatosis in which a single perforation in the terminal ileum was disclosed on laparotomy and active necrotizing vasculitis was found in the submucosal layer of the resected specimen.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Granulomatosis with Polyangiitis / complications*
  • Humans
  • Ileal Diseases / complications*
  • Intestinal Perforation / complications*
  • Male
  • Vasculitis / complications