Gliomatosis cerebri: A consensus summary report from the First International Gliomatosis cerebri Group Meeting, March 26-27, 2015, Paris, France

Pediatr Blood Cancer. 2016 Dec;63(12):2072-2077. doi: 10.1002/pbc.26169. Epub 2016 Jul 28.


Gliomatosis cerebri (GC) is a universally fatal extensive and diffuse infiltration of brain parenchyma by a glial tumor. Many aspects of this phenomenon remain unknown. The First International Gliomatosis cerebri Group Meeting had the following goals: refine the clinical and radiologic diagnostic criteria for GC, suggest appropriate diagnostic procedures, standardize tissue manipulation for histologic and molecular characterization, and prioritize relevant preclinical projects. Also, general treatment recommendations were outlined for the pediatric population. Importantly, this meeting was the starting point for meaningful collaborative international research projects. This review is a consensus summary of discussions shared and conclusions derived from this meeting.

Keywords: Gliomatosis cerebri; consensus; meeting.

Publication types

  • Review
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Brain Neoplasms / diagnosis
  • Brain Neoplasms / epidemiology
  • Brain Neoplasms / genetics
  • Brain Neoplasms / therapy*
  • Consensus
  • Epigenesis, Genetic
  • Humans
  • Neoplasms, Neuroepithelial / diagnosis
  • Neoplasms, Neuroepithelial / epidemiology
  • Neoplasms, Neuroepithelial / genetics
  • Neoplasms, Neuroepithelial / therapy*
  • Neuroimaging
  • Prognosis