Purpose: This study aims to evaluate the recurrence pattern of hepatocellular carcinoma (HCC) following liver transplantation.
Materials and methods: A total of 54 patients underwent liver transplantation for HCC; 9 patients developed biopsy-proven recurrent HCC (16.6%). The site of HCC recurrence along with other factors was analyzed.
Results: Seven patients were diagnosed with HCC prior to liver transplantation and 2 patients had incidental HCC in the explanted liver. Two patients had locoregional recurrence, 4 patients had distant metastasis, and 3 patients had synchronous locoregional recurrence and distant metastasis.
Conclusion: A significant proportion of HCC recurrence following liver transplantation is extrahepatic.
Keywords: HCC; Hepatocellular carcinoma; Liver transplantation; Metastasis; Surveillance.
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