Brief Report: Early VEPs to Pattern-Reversal in Adolescents and Adults with Autism

J Autism Dev Disord. 2016 Oct;46(10):3377-86. doi: 10.1007/s10803-016-2880-8.


Autism spectrum disorder (ASD) is characterized by atypical visual perception both in the social and nonsocial domain. In order to measure a reliable visual response, visual evoked potentials were recorded during a passive pattern-reversal stimulation in adolescents and adults with and without ASD. While the present results show the same age-related changes in both autistic and non-autistic groups, they reveal a smaller P100 amplitude in the ASD group compared to controls. These results confirm that early visual responses are affected in ASD even with a simple, non social and passive stimulation and suggest that they should be considered in order to better understand higher-level processes.

Keywords: Autism spectrum disorder; Pattern-reversal paradigm; Sensory symptoms; Visual evoked potentials.

MeSH terms

  • Adolescent
  • Adult
  • Autistic Disorder / diagnosis*
  • Autistic Disorder / physiopathology*
  • Autistic Disorder / psychology
  • Evoked Potentials, Visual / physiology*
  • Female
  • Humans
  • Male
  • Pattern Recognition, Visual / physiology*
  • Photic Stimulation / methods*
  • Visual Perception / physiology
  • Young Adult