Alpha-blockers for the Treatment of Benign Prostatic Hyperplasia

Urol Clin North Am. 2016 Aug;43(3):311-23. doi: 10.1016/j.ucl.2016.04.009.

Abstract

Over the last 2 decades the evolution of alpha-blockers for lower urinary tract symptoms (LUTS)/benign prostatic hyperplasia (BPH) has been to preserve effectiveness, improve tolerability, and eliminate dose titration. Today, alpha-blockers represent the first-line treatment of most men with BPH whereby the primary objective is relief from bothersome LUTS.

Keywords: Alpha-blockers; BPH; Lower urinary tract symptoms; Medical management BPH.

Publication types

  • Review

MeSH terms

  • Adrenergic alpha-Antagonists / therapeutic use*
  • Humans
  • Lower Urinary Tract Symptoms / drug therapy*
  • Lower Urinary Tract Symptoms / etiology
  • Lower Urinary Tract Symptoms / physiopathology
  • Male
  • Prostatic Hyperplasia / complications
  • Prostatic Hyperplasia / drug therapy*
  • Urodynamics / drug effects

Substances

  • Adrenergic alpha-Antagonists