Motor neuropathy with multifocal conduction blocks

Muscle Nerve. 1989 Jan;12(1):26-31. doi: 10.1002/mus.880120106.


We describe a patient with a chronic, symmetric, monophasic, acquired, pure motor, demyelinating polyneuropathy. Electrodiagnostic studies showed the presence of multifocal conduction blocks in motor nerves at sites not prone to compression. A sural nerve biopsy was normal. The patient responded to immunosuppressive therapy and plasma exchange. We postulate that this disorder is an unusual variant of chronic inflammatory polyradiculoneuropathy.

MeSH terms

  • Adolescent
  • Electrophysiology
  • Female
  • Humans
  • Motor Neurons / physiology*
  • Neural Conduction
  • Neuromuscular Diseases / physiopathology*