Tailoring mass drug administration to context: implementation research is critical in achieving equitable progress in the control and elimination of helminth neglected tropical diseases in sub-Saharan Africa

Int Health. 2016 Jul;8(4):233-4. doi: 10.1093/inthealth/ihw031.


The concept of a technological quick fix or 'magic-bullet' for control and elimination of Neglected Tropical Diseases (NTDs) is flawed. NTDs are embedded within complex biological and social systems that are shaped by ecological and political contexts. This commentary emphasises the need for implementation research to address implementation gaps in the control of NTDs. With a specific focus on sub-Saharan Africa and helminth diseases amenable to preventive chemotherapy through mass drug administration, we explore the important role of context, programme partnerships and community in achieving equitable and effective NTD control.

Keywords: Equity; Implementation Research; Mass Drug Administration; Neglected Tropical Diseases.

MeSH terms

  • Africa South of the Sahara / epidemiology
  • Animals
  • Chemoprevention / methods*
  • Communicable Disease Control / methods*
  • Communicable Diseases / epidemiology
  • Helminthiasis / epidemiology
  • Helminthiasis / prevention & control*
  • Helminths / parasitology*
  • Humans
  • Mass Vaccination*
  • Neglected Diseases / epidemiology
  • Neglected Diseases / prevention & control*
  • Tropical Medicine / methods*