Looking to the future following 10 years of induced pluripotent stem cell technologies

Nat Protoc. 2016 Sep;11(9):1579-85. doi: 10.1038/nprot.2016.108. Epub 2016 Aug 4.


The development of induced pluripotent stem cells (iPSCs) has fundamentally changed our view on developmental cell-fate determination and led to a cascade of technological innovations in regenerative medicine. Here we provide an overview of the progress in the field over the past decade, as well as our perspective on future directions and clinical implications of iPSC technology.

Publication types

  • Review

MeSH terms

  • Animals
  • Cell Transdifferentiation
  • Cellular Reprogramming*
  • Cellular Senescence
  • Clinical Trials as Topic
  • Humans
  • Induced Pluripotent Stem Cells / cytology*