Redundancy and specificity in jasmonate signalling

Curr Opin Plant Biol. 2016 Oct;33:147-156. doi: 10.1016/j.pbi.2016.07.005. Epub 2016 Aug 1.

Abstract

Jasmonates (JAs) are essential phytohormones regulating plant development and environmental adaptation. Many components of the JA-signalling pathway have been identified. However, our insight into the mechanisms by which a single bioactive JA hormone can regulate a myriad of physiological processes and provide specificity in the response remains limited. Recent findings on molecular components suggest that, despite apparent redundancy, specificity is achieved by (1) distinct protein-protein interactions forming unique JAZ/transcription factor complexes, (2) discrete spatiotemporal expression of specific components, (3) variable hormone thresholds for the formation of multiple JA receptor complexes and (4) integration of several signals by JA-pathway components. The molecular modularity that is thereby created enables a single bioactive hormone to specifically modulate multiple JA-outputs in response to different environmental and developmental cues.

Publication types

  • Review
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Arabidopsis / genetics
  • Arabidopsis / physiology*
  • Arabidopsis Proteins / genetics*
  • Arabidopsis Proteins / metabolism
  • Cyclopentanes / metabolism*
  • Gene Expression Regulation, Plant*
  • Oxylipins / metabolism*
  • Plant Growth Regulators / metabolism*
  • Signal Transduction*

Substances

  • Arabidopsis Proteins
  • Cyclopentanes
  • Oxylipins
  • Plant Growth Regulators
  • jasmonic acid