Tobacco exposure and maternal psychopathology: Impact on toddler problem behavior

Neurotoxicol Teratol. 2016 Sep-Oct:57:87-94. doi: 10.1016/j.ntt.2016.07.003. Epub 2016 Aug 3.

Abstract

Prenatal exposure to tobacco has consistently predicted later problem behavior for children. However, little is known about developmental mechanisms underlying this association. We examined a conceptual model for the association between prenatal tobacco exposure and child problem behavior in toddlerhood via indirect paths through fetal growth, maternal depression, and maternal aggressive disposition in early infancy and via maternal warmth and sensitivity and infant negative affect in later infancy. The sample consisted of 258 mother-child dyads recruited during pregnancy and assessed periodically at 2, 9, and 16months of child age. Pathways via maternal depression and infant negative affect to toddler problem behavior were significant. Further, combined tobacco and marijuana exposure during pregnancy and reduced fetal growth also demonstrated important associations with infant negative affect and subsequent problem behavior. These results highlight the importance of considering the role of maternal negative affect and poor fetal growth as risk factors in the context of prenatal exposure.

Keywords: Maternal psychopathology; Prenatal marijuana/cannabis exposure; Prenatal tobacco exposure; Problem behavior.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Adult
  • Aggression
  • Cannabis / adverse effects
  • Child Behavior / drug effects
  • Child, Preschool
  • Female
  • Fetal Development / drug effects
  • Humans
  • Infant
  • Male
  • Maternal Behavior*
  • Mother-Child Relations
  • Mothers / psychology*
  • Pregnancy
  • Prenatal Exposure Delayed Effects / psychology*
  • Problem Behavior*
  • Sex Factors
  • Tobacco Products
  • Young Adult