Subclinical hypothyroidism causing hypertension in pregnancy

J Am Soc Hypertens. 2016 Sep;10(9):691-3. doi: 10.1016/j.jash.2016.06.039. Epub 2016 Jul 18.

Abstract

This is a case of a 25-year-old primigravida who was referred to the hypertension specialist for elevated blood pressures. The patient had an elevated thyroid-stimulating hormone with normal free thyroxine (T4) levels and was positive for thyroid peroxidase antibodies resulting in a diagnosis of subclinical hypothyroidism. The patient was successfully treated with levothyroxine which normalized the blood pressure without the need for antihypertensive treatment. This case illustrates a cause of secondary hypertension that is not always considered in the differential diagnosis of a patient with hypertension in pregnancy.

Keywords: Hypertension; pregnancy; subclinical hypothyroidism.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Antihypertensive Agents / administration & dosage
  • Antihypertensive Agents / therapeutic use
  • Autoantibodies / blood*
  • Diagnosis, Differential
  • Female
  • Humans
  • Hypertension / blood
  • Hypertension / diagnosis
  • Hypertension / drug therapy
  • Hypertension / etiology*
  • Hypertension, Pregnancy-Induced / diagnosis
  • Hypothyroidism / blood
  • Hypothyroidism / complications
  • Hypothyroidism / drug therapy*
  • Methyldopa / administration & dosage
  • Methyldopa / therapeutic use
  • Pregnancy
  • Referral and Consultation
  • Thyrotropin / blood
  • Thyroxine / blood
  • Thyroxine / therapeutic use*

Substances

  • Antihypertensive Agents
  • Autoantibodies
  • thyroid microsomal antibodies
  • Methyldopa
  • Thyrotropin
  • Thyroxine