Bilateral cleft foot: Radiographic and prenatal ultrasound features of two siblings with a review of literature

Medicina (Kaunas). 2016;52(4):257-261. doi: 10.1016/j.medici.2016.07.003. Epub 2016 Jul 26.


Cleft foot deformity, also known as ectrodactyly, is a rare congenital developmental defect of extremities caused by malformation in continuity of apical ectoderm. The syndrome typically involves malformation or absence of the central rays of the feet and is characterized by deformities like median deep clefts of distal extremities. Routine examination of feet during second-trimester ultrasound (US) may increase the detection rates of foot malformations. Many malformations can be diagnosed with 2-dimensional (2D) US, but 3-dimensional (3D) US also helps better understanding of the foot malformations. In the present study, we report the case of two brothers (a fetus and a 5-year-old) with cleft foot deformity. 2D and 3D second trimester US findings of one case and the foot radiography findings of the other are presented here.

Keywords: Cleft foot malformation; Fetal foot; Obstetric ultrasound; Prenatal diagnosis.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Child, Preschool
  • Female
  • Fetus / abnormalities*
  • Fetus / diagnostic imaging
  • Foot Deformities, Congenital / diagnostic imaging*
  • Humans
  • Imaging, Three-Dimensional
  • Limb Deformities, Congenital / diagnostic imaging*
  • Male
  • Metatarsal Bones / abnormalities*
  • Metatarsal Bones / diagnostic imaging
  • Polydactyly / diagnostic imaging
  • Pregnancy
  • Pregnancy Trimester, Second
  • Siblings
  • Ultrasonography, Prenatal

Supplementary concepts

  • Ectrodactyly