Chagas Disease: A Solvable Problem, Ignored

Trends Mol Med. 2016 Oct;22(10):835-838. doi: 10.1016/j.molmed.2016.07.008. Epub 2016 Aug 11.


Chagas disease is the highest impact parasitic disease in the Americas, yet remains virtually unknown and untreated, despite the fact that the infection is curable and the global problem of Chagas disease is manageable. The causes of this situation and how it can be changed are the focus of this communication.

Keywords: Chagas disease; Trypanosoma cruzi.; drug discovery; neglected diseases.

MeSH terms

  • Animals
  • Chagas Disease / drug therapy*
  • Clinical Trials as Topic
  • Drug Discovery* / methods
  • Humans
  • Neglected Diseases / drug therapy
  • Trypanocidal Agents / pharmacology
  • Trypanocidal Agents / therapeutic use*
  • Trypanosoma cruzi / drug effects*


  • Trypanocidal Agents