Repositioning 'old' drugs to treat rare diseases: arguing from the mechanism of action

Sarcoidosis Vasc Diffuse Lung Dis. 2016 Aug 1;33(2):191-4.
No abstract available

Keywords: histiocytosis-X, orphan drugs, pharmacological treatment, rare disease.

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Administration, Oral
  • Aminopyridines / administration & dosage*
  • Benzamides / administration & dosage*
  • Cyclopropanes / administration & dosage
  • Drug Repositioning*
  • Evidence-Based Medicine
  • Female
  • Histiocytosis, Langerhans-Cell / diagnosis
  • Histiocytosis, Langerhans-Cell / drug therapy*
  • Histiocytosis, Langerhans-Cell / physiopathology
  • Humans
  • Middle Aged
  • Orphan Drug Production*
  • Phosphodiesterase 4 Inhibitors / administration & dosage*
  • Rare Diseases / drug therapy*
  • Tomography, X-Ray Computed
  • Treatment Outcome

Substances

  • Aminopyridines
  • Benzamides
  • Cyclopropanes
  • Phosphodiesterase 4 Inhibitors
  • Roflumilast