Spontaneous, headshaking, and positional nystagmus in post-lateral medullary infarction dizziness

Abstract

Background and purpose: Lateral medullary infarction (LMI) sometimes causes long-lasting dizziness. However, the characteristics of nystagmus in patients with post-LMI dizziness are unknown. We undertook a prospective, comparative study of nystagmus in patients with and without post-LMI dizziness to determine the characteristic pattern of nystagmus of chronic post-LMI dizziness.

Methods: We evaluated and compared nystagmus under spontaneous, head-shaking, and positional testing conditions in 12 patients with post-LMI dizziness and in 6 patients without post-LMI dizziness.

Results: In the dizziness group, contralateral spontaneous nystagmus, ipsilateral head-shaking nystagmus, and horizontal direction-changing geotropic positional nystagmus were observed in patients in whom the LMI had occurred <60days previously (subacute period). In patients with dizziness in whom the LMI had occurred >90days previously (chronic period), the nystagmus was ipsilateral under all conditions. In the non-dizziness group, ipsilateral nystagmus was observed in 1 of the 2 subacute patients only after head-shaking and in 1 of the 4 chronic patients only during positional testing.

Conclusions: Ipsilateral nystagmus observed under all spontaneous, head-shaking, and positional testing conditions characterizes chronic post-LMI dizziness.

Keywords: Dizziness; Head-shaking nystagmus; Lateral medullary infarction; Positional nystagmus; Spontaneous nystagmus.