Do not throw the baby out with the bath water: a guide for using non-significant results in practice

Evid Based Med. 2016 Oct;21(5):161-2. doi: 10.1136/ebmed-2016-110510. Epub 2016 Aug 18.


Acting on results that are not statistically significant is challenging for clinicians. Such results are often interpreted as evidence of lack of association or as useless evidence. We provide a framework for interpreting and applying non-significant results at the point of care using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach.

Keywords: EDUCATION & TRAINING (see Medical Education & Training); EPIDEMIOLOGY; OBSTETRICS.

MeSH terms

  • Evidence-Based Medicine*
  • Practice Guidelines as Topic*