Diagnosis, Cause, and Treatment Approaches for Delayed Sleep-Wake Phase Disorder

Michelle Magee; Emily M Marbas; Kenneth P Wright Jr; Shantha M W Rajaratnam; Josiane L Broussard

doi:10.1016/j.jsmc.2016.05.004

Diagnosis, Cause, and Treatment Approaches for Delayed Sleep-Wake Phase Disorder

Sleep Med Clin. 2016 Sep;11(3):389-401. doi: 10.1016/j.jsmc.2016.05.004. Epub 2016 Jul 16.

Authors

Michelle Magee¹, Emily M Marbas², Kenneth P Wright Jr², Shantha M W Rajaratnam³, Josiane L Broussard²

Affiliations

¹ Cooperative Research Centre for Alertness, Safety and Productivity, School of Psychological Sciences, Monash University, BASE Facility, Ground Level 264 Ferntree Gully Road, Notting Hill, Victoria 3168, Australia; Monash Institute of Cognitive and Clinical Neurosciences, Monash University, 18 Innovation Walk, Wellington Road, Clayton, Victoria 3800, Australia. Electronic address: michelle.magee@monash.edu.
² Sleep and Chronobiology Laboratory, Department of Integrative Physiology, University of Colorado, 1725 Pleasant Street, Clare Small 114, Boulder, CO 80309-0354, USA.
³ Cooperative Research Centre for Alertness, Safety and Productivity, School of Psychological Sciences, Monash University, BASE Facility, Ground Level 264 Ferntree Gully Road, Notting Hill, Victoria 3168, Australia; Monash Institute of Cognitive and Clinical Neurosciences, Monash University, 18 Innovation Walk, Wellington Road, Clayton, Victoria 3800, Australia; Division of Sleep and Circadian Disorders, Departments of Medicine and Neurology, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115, USA; Division of Sleep Medicine, Harvard Medical School, 25 Shattuck Street, Boston, MA 02115, USA.

PMID: 27542884
DOI: 10.1016/j.jsmc.2016.05.004

Abstract

Delayed sleep-wake phase disorder (DSWPD) is commonly defined as an inability to fall asleep and wake at societal times resulting in excessive daytime sleepiness. Although the cause is multifaceted, delays in sleep time are largely driven by misalignment between the circadian pacemaker and the desired sleep-wake timing schedule. Current treatment approaches focus on correcting the circadian delay; however, there is a lack of data investigating combined therapies for treatment of DSWPD.

Keywords: Bright light; Circadian phase; Circadian rhythms; Delayed sleep; Delayed sleep phase; Homeostat; Melatonin; Phototherapy.

Publication types

Review

MeSH terms

Humans
Sleep Disorders, Circadian Rhythm* / diagnosis
Sleep Disorders, Circadian Rhythm* / etiology
Sleep Disorders, Circadian Rhythm* / therapy