Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Randomized Controlled Trial
. Jul-Aug 2016;68(4):498-506.
doi: 10.1016/j.ihj.2015.10.384. Epub 2016 Jan 13.

A Randomized Study of Coconut Oil Versus Sunflower Oil on Cardiovascular Risk Factors in Patients With Stable Coronary Heart Disease

Affiliations
Free PMC article
Randomized Controlled Trial

A Randomized Study of Coconut Oil Versus Sunflower Oil on Cardiovascular Risk Factors in Patients With Stable Coronary Heart Disease

Maniyal Vijayakumar et al. Indian Heart J. .
Free PMC article

Abstract

Background and rationale: Coronary artery disease (CAD) and its pathological atherosclerotic process are closely related to lipids. Lipids levels are in turn influenced by dietary oils and fats. Saturated fatty acids increase the risk for atherosclerosis by increasing the cholesterol level. This study was conducted to investigate the impact of cooking oil media (coconut oil and sunflower oil) on lipid profile, antioxidant mechanism, and endothelial function in patients with established CAD.

Design and methods: In a single center randomized study in India, patients with stable CAD on standard medical care were assigned to receive coconut oil (Group I) or sunflower oil (Group II) as cooking media for 2 years. Anthropometric measurements, serum, lipids, Lipoprotein a, apo B/A-1 ratio, antioxidants, flow-mediated vasodilation, and cardiovascular events were assessed at 3 months, 6 months, 1 year, and 2 years.

Results: Hundred patients in each arm completed 2 years with 98% follow-up. There was no statistically significant difference in the anthropometric, biochemical, vascular function, and in cardiovascular events after 2 years.

Conclusion: Coconut oil even though rich in saturated fatty acids in comparison to sunflower oil when used as cooking oil media over a period of 2 years did not change the lipid-related cardiovascular risk factors and events in those receiving standard medical care.

Keywords: Atherosclerosis; Cholesterol; Coconut oil; Cooking medium; Sunflower oil.

Figures

Fig. 1
Fig. 1
Randomization, allocation, follow-up, and analysis.

Similar articles

See all similar articles

Cited by 9 articles

See all "Cited by" articles

References

    1. Stamler J., Wentworth D., Neaton J.D. Is relationship between serum cholesterol and risk of premature death from coronary heart disease continuous and graded? Findings in 356,222 primary screeners of the Multiple Risk Factor Intervention Trial (MRFIT) JAMA. 1986;256:2823–2828. - PubMed
    1. Neaton J.D., Blackburn H., Jacobs D. Serum cholesterol level and mortality findings for men screened in the Multiple Risk Factor Intervention Trial. Multiple Risk Factor Intervention Trial Research Group. Arch Intern Med. 1992;152:1490–1500. - PubMed
    1. Lloyd-Jones D.M., Wilson P.W., Larson M.G. Framingham risk score and prediction of lifetime risk for coronary heart disease. Am J Cardiol. 2004;94:20–24. - PubMed
    1. Musunuru K. Atherogenic dyslipidemia: cardiovascular risk and dietary intervention. Lipids. 2010;45:907–914. - PMC - PubMed
    1. Mensink R.P., Zock P.L., Kester A.D., Katan M.B. Effects of dietary fatty acids and carbohydrates on the ratio of serum total to HDL cholesterol and on serum lipids and apolipoproteins: a meta-analysis of 60 controlled trials. Am J Clin Nutr. 2003;77:1146–1155. - PubMed

Publication types

Feedback