Digitally deconvolving the tumor microenvironment

Genome Biol. 2016 Aug 22;17(1):175. doi: 10.1186/s13059-016-1036-7.


Understanding a tumor's complex cellular heterogeneity will be crucial for the development of better treatment strategies. A new study suggests a novel method for the in silico dissociation of solid tumors and presents novel insights that have implications for immunotherapy in cancer.Please see the related Research article: .

Publication types

  • Review
  • Research Support, N.I.H., Extramural
  • Comment

MeSH terms

  • Combined Modality Therapy
  • Computer Simulation*
  • Genetic Therapy
  • Humans
  • Immunotherapy / methods
  • Models, Biological*
  • Molecular Targeted Therapy
  • Neoplasms / etiology*
  • Neoplasms / pathology*
  • Neoplasms / therapy
  • Tumor Microenvironment*